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Enzymes play a central role in all metabolic and cellular pathways. The Versées lab therefore focuses on the elucidation of the mechanisms that underlie the tremendous catalytic power and regulation of enzymes and enzyme complexes.

The genomes of lost bacteria contain a plethora of small operons commonly referred to as toxin- antitoxin (TA) systems. The toxin typically slows down or almost completely halts bacterial metabolism as a consequence of various kinds of stress such as food limitations.

The DNA Damage Response (DDR) is a large signaling network that senses and responds to different types of DNA damage. It controls DNA repair, cell cycle progression, apoptosis and all other responses to replication stress.

The mission of the Messens lab is to decipher how cells communicate via H2 O2 and metabolite signals and how cells transduce these messages into downstream biological effects. We are studying the mechanisms behind reactive oxygen species scavenging, signaling, and regulation.

As artificial intelligence (AI) tools employ more advanced reasoning mechanisms and computation, it becomes increasingly difficult to understand why certain decisions are made.

Answer set programming (ASP) is a formalism in which combinatorial (optimization) problems can be modeled easily, due to a well- developed first-order modeling language. For this language, efficient solvers have been developed.

 I am interested in research on unifying frameworks in the domain of knowledge representation and reasoning. Of particular interest are: approximation fixpoint theory and justification theory (and especially: investigating the relation between these two).

Research towards efficient algorithms for combinatorial search, in domains such as answer set programming, Boolean satisfiability, Quantified Boolean Formulas, Constraint Programming, Pseudo-Boolean solving and Mixed Integer Programming is greatly valued in my lab.

Abstract: University governance and leadership has become an important issue and a core research topic in recent years.

Abstract: Blended learning integrating innovative use of technologies and face-to-face education has become an important education innovation in the modern society.